Education:

1979-1984 M.D. Fujian Medical College (P. R. China)
1984-1987 M.Sc. (Pharmacology) Suzhou Medical College (P. R. China)
1989-1991 Ph.D. Candidate (Cell Biology) Baylor College of Medicine
1989-1992 Ph.D. (Cell Biology) Duke University
1993-1996 Research Associate, Molecular Biology, Salk Institute

Research and Teaching Interests:
      Our primary research interest is to understand the fundamental mechanisms of aging and age-related disease.  Specifically, we have discovered three human genes (Pin1, Pin2/TRF1 and PinX1) that play major regulatory roles in aging and age-related disease. Our studies establish a new paradigm in cell signaling, uncover new pathogenic mechanisms and also point to potentially novel therapeutic strategies for human disease, notably cancer and Alzheimer’s disease, major age-related diseases.